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Confirmatory secondary endpoints included relative change in bodyweight (%) from baseline to week 40

GLP-1 Medications: The Metabolic Component GLP-1 receptor agonists (semaglutide, tirzepatide, liraglutide) are the metabolic backbone of this stack

Usage Guidelines: The addition of medication should be performed using complete aseptic technique

This association was observed across all three models, including the unadjusted model ( = 0.010, 95% CI -0.016 to 0.005), adjusted model I ( = 0.007, 95% CI -0.013 to 0.002), and adjusted model II ( = 0.008, 95% CI -0.014 to 0.002)