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Moreover, Syn-S129p triggers protein-protein interactions by inducing conformational changes within the C-terminal region, which are essential for mediating Syn function at the synapse and within the nucleus 71,73,89

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Die Vitamine B6 (Pyridoxin), B9 (Folsure) und B12 spielen zudem eine zentrale Rolle bei der Herstellung der Aminosure Methionin, die als Ausgangsstoff fr die Glutathionbildung bentigt wird

The AKT/mTOR hyperactivation in these organoids suggests that mTOR inhibitors (e.g., rapamycin analogs) may ameliorate synaptic imbalances, warranting clinical exploration in ASD subtypes with CNTNAP2 mutations

This Lp(a) driven inflammation leads to endothelial dysfunction.[ref] Specifically, lipoprotein(a) and ApoA covalently bind with oxidized phospholipids at the site of distress or lesions in the endothelium