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For the vast majority of patients with type 2 diabetes, the metabolic advantages clearly outweigh any potential bone-related risks

We also discuss combination therapies and strategies to mitigate muscle mass loss during treatment and calls for targeted research, improved clinical education, and policy reforms to optimize the translational potential of GLP-1R agonists in both individualized care and population health

Beyond the clinical data, the emotional impact - regaining control over eating habits, seeing the scale move, and feeling heard by providers - is central to the program's appeal

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Cases have required hospitalization