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[3] [8] If removed from refrigeration, a tirzepatide pen may be kept at room temperature (up to 86F or 30C) for up to 21 days before use

Vigorously shaking a reconstituted peptide can damage the delicate amino acid chains, potentially rendering it less effective or completely inert

This finding could lead to new guidelines to treat T1D in adults if replicated in a randomized trial

You use it when the swallowing difficulty is specified but doesn't match the oral, oropharyngeal, pharyngeal, or pharyngoesophageal phases

GLP-1R agonists and SGLT-2 inhibitors are promising tools in our therapeutic armamentarium in this setting [111113] (Figure 1)