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The only patients who could use the drugs were those willing to pay out of pocket

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Simultaneously, GLP-1 receptor activation stimulates glucose-dependent insulin release from pancreatic beta cells, suppresses inappropriate glucagon secretion, slows gastric emptying, and promotes satiety through central nervous system pathways

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Abbreviations GLP-1 RAs: Glucagon-like peptide-1 receptor agonists T2DM: Type 2 diabetes mellitus COPD: Chronic obstructive pulmonary disease BMI: Body mass index HbA1c: Glycated hemoglobin RR: Relative risk CI: Confidence interval RCT: Randomized controlled trial CVOT: Cardiovascular outcome trial PRISMA: Preferred reporting items for systematic reviews and meta-analyses References Zar HJ, Ferkol TW