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Losing muscle along with fat produces a worse metabolic outcome long-term

Dosing Protocol Suggested daily titration approach based on clinical studies [2][3][4]

Table 11: Type 2 Diabetes Mellitus Adults Additional Clinical Studies In Adults with Diabetes Type 1 And Type 2 Different Timing Of Insulin Glargine Administration In Diabetes Type 1 And Diabetes Type 2 The safety and efficacy of once daily insulin glargine administered either at pre-breakfast, predinner, or at bedtime were evaluated in a randomized, controlled clinical study in adult patients with type 1 diabetes (Study H, n = 378)

Buller, S