Most of these are associated with adverse cardiovascular reactions (Sibutramine, Fenfluramine, Dexfenfluramine, Rainbow pills), increased risk of suicide (rimonabant), or increased drug dependence and abuse (methamphetamine)
It belongs to the biguanide class of drugs and works by reducing glucose production in the liver, improving insulin sensitivity in the body, and decreasing intestinal absorption of glucose
As it goes down, the risk of fractures goes up
Nat Rev Drug Discov 9:551559 Trujillo JM, Nuffer WA (2017) Impact of sodium-glucose cotransporter 2 inhibitors on Nonglycemic outcomes in patients with type 2 diabetes
Feel full, not tempted Carolean and wakame support natural GLP-1 release and help reduce hunger in the evening