first day taking tirzepatide injection experience — 1 personal reaction First month on Tirz, dosing

I just mentioned a post-diagnosis weight gain of over 10% is associated with worse outcomes, so if that 5% weight loss can be combined with additional lifestyle factors, that gets towards attenuating that weight gain that patients may see and can be meaningful in terms of patients quality of life, how they tolerate their endocrine therapies, how they feel, and their body image

Piece by piece, a building comes together, but if one brick falls out of line, the whole system can crumble

Shankar SS, Shankar RR, Mixson LA, et al

persistent cortisol elevation nudges the body toward abdominal storage and slows visceral mobilization

This mechanical irritation may be exacerbated by improper injection technique, including injecting too rapidly, using a dull needle, or failing to allow the medication to reach room temperature before administration