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Clinically, B12 shots have long been used to treat cyanide poisoning

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The b12 overdose treatment depends on how severe the symptoms are and why the levels are high: Stop B12 supplements Adjust your diet Pay attention to signs and symptoms of b12 overdose Talk to a doctor or dietitian for personalized advice Treat underlying conditions Have regular blood tests Vitamin B12 Dosage for Adults For most adults, a daily intake of 2.4 micrograms of vitamin b12 interaction is sufficient