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Skin and Extracellular Matrix Research Epithalon has been studied in connective tissue and skin-related models focusing on fibroblast function and extracellular matrix integrity: Rodent studies indicate that Epithalon may increase fibroblast activation and proliferation parameters, with reported relative increases in fibroblast activity in certain skin models

Augmented autophagy pathways and MTOR modulation in fibroblasts from long-lived mutant mice

10.1093/toxsci/kfq039

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