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Briefly, transfected HEK293T, CL1-0, and H1299 cells were lysed on ice for 510 min in a solution containing 20 mM Tris (pH 8.0), 150 mM NaCl, 100 M Na 3 VO 4 , 50 mM NaF, 30 mM sodium pyrophosphate, 0.5% NP-40 (Sigma-Aldrich), and a 25-fold dilution of a stock solution was treated with one Mini Protease Inhibitor Cocktail Tablet (Roche, #10061200-4) dissolved in 2 ml of PBS

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(Photo credit: AI generated) Simran Arora Updated Apr 28, 2026 | 02:59 PM IST Summary Current research suggests that retatrutide may lead to greater weight loss than other drugs on the market, but potentially at a high cost