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Sitagliptin is a substrate for human organic anion transporter-3 (hOAT-3), which may be involved in the renal elimination of sitagliptin

When treatment ends, those effects gradually fade, which can make weight regain more likely without a long-term maintenance plan

Cell Metab (2016) 24(1):6374.10.1016/j.cmet.2016.06.016 179 GomezAPetrzelkovaKJBurnsMBYeomanCJAmatoKRVlckovaKet alGut microbiome of coexisting BaAka pygmies and Bantu reflects gradients of traditional subsistence patterns