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Energy and Mood: TRT is known to improve energy levels and mental health, which may complement semaglutides role in promoting physical health by supporting patients motivation to stick to healthy habits

Further considerations include: Dehydration risk : Combined effects of diarrhoea (from both Crohn's and medication) may increase dehydration risk Medication absorption : While generally minimal, delayed gastric emptying could affect absorption of oral medications with a narrow therapeutic index Monitoring requirements : Regular assessment of disease activity markers, nutritional status, and weight trends is essential Patients should be counselled about these risks and encouraged to report any worsening gastrointestinal symptoms promptly to the MHRA Yellow Card scheme (yellowcard.mhra.gov.uk), as distinguishing between expected side effects and disease progression requires clinical expertise

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While it's not 100% waterproof, it's made from sweat- and splash-resistant materials to protect your valuables