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2014;8(262275):e9

Liraglutide fall in the middle with 30-day stability at room temperature

Patients should not panic if appetite changes

N Engl J Med (2021) 385(1):e4

Historically, such behavioral complexity was viewed as a disqualifying feature for drug development, as CNS-acting agents were associated with unpredictable neuropsychiatric liability and high regulatory barriers ( 5.4 Translational lessons from abandoned appetite peptides The historical trajectory of appetite and behavioral peptides reveals a recurring pattern: early development efforts often failed due to inadequate control over exposure, insufficient combination strategies, or overly conservative interpretations of side effects