Its regulation affects sleep continuity, REM sleep patterns, and has implications for the therapeutic mechanisms of antidepressants, highlighting its importance in both the manifestation of insomnia and its potential as a target for preventing depression linked to sleep disturbances ( Dopamine plays a crucial role in the transition from nonrapid eye movement (NREM) sleep to rapid eye movement (REM) sleep through a transient increase in the basolateral amygdala (BLA), acting on D2 dopamine receptors to initiate the NREM-to-REM shift
It might be an enzyme you have never heard of, one that is actively working against your fat loss efforts at the cellular level
The 2025 IV pilot measured cardiac, hepatic, renal, thyroid, and glucose biomarkers and reported no abnormalities (Lee et al., 2025), which gives a sense of what those investigators considered worth checking
BMJ Open 10 (8), e033687
Strength of the Association of elevated vitamin B12 and solid cancers: An adjusted case-control study
