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Several promising compounds have failed in clinical trials due to a range of challenges, including inadequate disease models, late intervention timing, insufficient biomarker validation, and difficulty in distinguishing symptomatic from neuroprotective effects

GenePattern, a publicly available computational biology open-source software package developed for the analysis of genomic data, was used to analyze the gene data obtained from the cMap

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These infections, while historically significant contributors to global dementia burden, remain clinically relevant even in developed countries

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