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While injectable GLP-1 receptor agonists such as semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound) have transformed the treatment landscape for obesity and type 2 diabetes, their reliance on subcutaneous injection remains a significant barrier to broader adoption

The primer sequences are summarized in Table 2

USA 110 , 1202412029 (2013)

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Telemedicine Practice Standards States Regulate: Consultation Requirements: Some states require live video or phone (not just messaging) Others allow asynchronous (message-based) consultations Documentation requirements vary Patient consent forms differ Prescribing Standards: What can be prescribed via telehealth Whether initial in-person visit required (rare for weight loss now) Documentation needed in medical record Follow-up requirements Examples of State Variations: More Restrictive States: May require video consultation (not just questionnaire) Additional documentation requirements More stringent informed consent Limitations on initial prescribing More Permissive States: Allow asynchronous consultations Streamlined documentation Fewer restrictions on telehealth prescribing Legitimate providers comply with each states specific requirements