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Prunes and kiwifruit have specific evidence supporting their laxative effects and can be incorporated into daily diet

The functions of amylin are complementary to insulin and to GLP-1 : Slows gastric emptying , similarly to GLP-1, but more strongly Suppresses glucagon , helps control postprandial glycemia Induces satiety , via the area postrema in the brainstem Regulates weight balance , long-term effect In type 2 diabetes amylin secretion deteriorates in parallel with insulin secretion , as the disease progresses, the -cells lose the ability to produce both hormones at once

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Although the harmful effects of MetS on the CNS are less severe than those of stroke, they are subclinical and chronic, involving a long period of inflammation from a multifactorial source