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Insulin receptors in the brain are located mainly in synapses and can be found in the hippocampus, entorhinal cortex, and frontal cortex, where insulin signaling leads to synaptogenesis and synaptic remodeling [70]

The harvested hearts were preserved in cold cardioplegia solution, and collected samples were snap-frozen in liquid nitrogen within 15 min of explantation and stored at 80C

doi: 10.1016/j.redox.2021.101930 113 SaltiTBraunsteinIHaimovichYZivTBenharM

Toxicity study of 28-day subcutaneous injection of arctigenin in Beagle Dogs