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2024;103(8):e209817

The rapid increase in cases of diabetes mellitus, especially T2D, raises concerns, also highlighting an urgent need to investigate effective therapies to curb this disease (King and Brownlee, 1996

Briefly, each mouse was injected subcutaneously with 2 g -estradiol benzoate solution (Sigma, #E2758) on days 1, 4, and 7

The leap from animal model findings to confirmed human benefit is significant, and many compounds that show promise in preclinical research do not translate successfully to human medicine

Clin Chem 44:679681 Noureddin M, Sander-Struckmeier S, Mato JM (2020) Early treatment efficacy of S-adenosylmethionine in patients with intrahepatic cholestasis: a systematic review