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For a 5 mg vial, adding 2.5 mL of bacteriostatic water creates a concentration of 2 mg per mL, or 0.2 mg per 0.1 mL

The FDA labeling recommends considering dose reduction of insulin or sulfonylureas when initiating tirzepatide to mitigate this risk

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Headache, mild fatigue, and a noticeable decrease in appetite are also listed among frequently reported Tirzepatide side effects in clinical trials