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On December 20, 2024, Eli Lilly announced the FDA has approved Zepbound (tirzepatide) as the first and only prescription medication for adults with moderate-to-severe obstructive sleep apnea and obesity. AASM.org Among persons with moderate-to-severe obstructive sleep apnea and obesity, tirzepatide reduced the AHI, body weight, hypoxic burden, hsCRP concentration, and systolic blood pressure and improved sleep-related patient-reported outcomes. NIH study Can the makers of these new weight loss medications really claim to treat and cure Obstructive Sleep Apnea (OSA)

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All weight loss leads to both fat and muscle loss, which can be a concern, especially in people who are already frail