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In line with a limited permeability of the OMM, the glutathione pool of the intermembrane space of mitochondria (IMS) was described to be maintained separately from the cytosolic glutathione pool (Hu et al , 2008)

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[DOI] [PubMed] [Google Scholar] 12.Borglum JD, Vassaux G, Richelsen B, Gaillard D, Darimont C, et al

But the good news is that Herxheimer reactions are typically temporary, and using some basic detoxification practices and supportive therapies is enough to get most people over the hump and back on more solid ground

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