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Vukojevic J, Milavic M, Perovic D, et al

The B12 will be given where the doctor recommends

This origin is what places MOTS-c in a separate research category from hGH-fragment or GHRH-analog compounds, since its activity is rooted in mitochondrial biology rather than the pituitary-hormone axis

Efficacy of Different Routes of Vitamin B12 Supplementation for the Treatment of Patients with Vitamin B12 Deficiency: A Systematic Review and Network Meta-Analysis. Irish Journal of Medical Science, 17 Jan

However, it never received FDA approval because the results, while positive, weren't dramatic enough to meet regulatory thresholds for an obesity drug