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Citrulline supplements actually increase arginine in the blood more than arginine itself, although this does not appear to increase NO production in healthy people with low but normal NO

To improve transparency, an adapted PRISMA-style flow diagram documenting identification, screening, eligibility assessment, de-duplication, and selection of the RCT evidence base and the proof-of-concept Bayesian subset is provided in the Supplementary Appendix Figure 1, together with details of the search strategy, screening process, and data extraction

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Long-term use of lysine may lead to arginine deficiency, which can cause serious health problems

Track any improvements in symptoms, changes in energy levels, or any new side effects