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Preclinical findings further suggest that GLP-1R activation engages the PI3K/Akt signaling cascade via the subunits of Gs proteins, influencing -cell viability and replicative capacity in research models

Additional strategies include promoting muscle growth through myostatin and activin blockade [34] as well as enhancing adipocyte lipolysis to induce fat reduction with drugs such as Vutiglabridin [24]

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