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Some IBS-M patients on GLP-1 therapy report that their diarrhoeal episodes became less frequent (a welcome change), but constipation phases became more pronounced

To accommodate retatrutides impact, begin workouts at times of peak energy with a calm stomach, as mild nausea and constipation may occur

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Transdermal products can cause local skin irritation, contact dermatitis, erythema (redness), pruritus (itching), or allergic sensitisation at the application site

A comprehensive meta-analysis of observational cohort studies by Celsa et al