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[2] Use of estradiol cypionate injection is contraindicated in individuals with undiagnosed abnormal vaginal bleeding, known or suspected breast cancer or other estrogen-dependent neoplasia, active or prior venous thromboembolism, recent arterial thrombo-occlusive disease such as stroke or myocardial infarction, severe hepatic impairment, a history of hypersensitivity to estradiol or any excipients, and in those who are or may become pregnant

It is purported to aid muscle growth and injury recovery

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Eisai submitted a new drug application in May 2015 but the Pharmaceuticals and Medical Devices Agency (PMDA) indicated that additional clinical trials were necessary

It also stimulates appetite and aids starch digestion, particularly in horses fed high-grain diets, ensuring that they receive the necessary nutrients to support their workload