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De novo loss-of-function mutations in SETD5, encoding a methyltransferase in a 3p25 microdeletion syndrome critical region, cause intellectual disability

GPX5 is synthesized primarily by epididymal head epithelial cells and secreted into the epididymal cavity to compensate for a deficiency of antioxidant enzymes in immature sperm (Lahti et al., 2001)

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